Calcinosis circumscripta

Changed by Daniel J Bell, 30 Nov 2021

Updates to Article Attributes

Body was changed:

Calcinosis circumscripta is a condition involving calcium deposition in the skin and subcutaneous tissues predominantly around joints and extremities 6. It is considered a localised form of calcinosis cutis most often seen in the hands and feet.

Clinical presentation

Patients present with firm white dermal papules, plaques or subcutaneous nodules which are found in varying distribution. They can ulcerate and extrude a chalky white material.

Classically, women are affected in up to 80% of cases.

Pathology

Aetiology

Although most cases are idiopathic there is an association with Raynaud syndrome, scleroderma or dermatomyositis in up to 40% of cases.

Radiographic features

Fine clustered calcifications are seen, usually around the finger and toe tips. If there is an associated underlying collagen vascular disease findings of soft tissue swelling and joint arthropathy may be present.

Differential diagnosis

All

  • -<p><strong>Calcinosis circumscripta</strong> is a condition involving calcium deposition in the skin and subcutaneous tissues predominantly around joints and extremities <sup>6</sup>. It is considered a localised form of <a href="/articles/calcinosis-cutis">calcinosis cutis</a> most often seen in the hands and feet.</p><h4>Clinical presentation</h4><p>Patients present with firm white dermal papules, plaques or subcutaneous nodules which are found in varying distribution. They can ulcerate and extrude a chalky white material.</p><p>Classically, women are affected in up to 80% of cases.</p><h4>Pathology</h4><h5>Aetiology</h5><p>Although most cases are idiopathic there is an association with <a href="/articles/raynaud-phenomenon">Raynaud syndrome</a>, <a href="/articles/scleroderma">scleroderma</a> or <a href="/articles/dermatomyositis">dermatomyositis</a> in up to 40% of cases.</p><h4>Radiographic features</h4><p>Fine clustered calcifications are seen, usually around the finger and toe tips. If there is an associated underlying <a title="Collagen vascular disease" href="/articles/connective-tissue-disease">collagen vascular disease</a> findings of soft tissue swelling and joint arthropathy may be present.</p><h4>Differential diagnosis</h4><p>All causes of <a href="/articles/soft-tissue-calcification-2">soft tissue calcification</a>.</p>
  • +<p><strong>Calcinosis circumscripta</strong> is a condition involving calcium deposition in the skin and subcutaneous tissues predominantly around joints and extremities <sup>6</sup>. It is considered a localised form of <a href="/articles/calcinosis-cutis">calcinosis cutis</a> most often seen in the hands and feet.</p><h4>Clinical presentation</h4><p>Patients present with firm white dermal papules, plaques or subcutaneous nodules which are found in varying distribution. They can ulcerate and extrude a chalky white material.</p><p>Classically, women are affected in up to 80% of cases.</p><h4>Pathology</h4><h5>Aetiology</h5><p>Although most cases are idiopathic there is an association with <a href="/articles/raynaud-phenomenon">Raynaud syndrome</a>, <a href="/articles/scleroderma">scleroderma</a> or <a href="/articles/dermatomyositis">dermatomyositis</a> in up to 40% of cases.</p><h4>Radiographic features</h4><p>Fine clustered calcifications are seen, usually around the finger and toe tips. If there is an associated underlying <a href="/articles/connective-tissue-disease">collagen vascular disease</a> findings of soft tissue swelling and joint arthropathy may be present.</p><h4>Differential diagnosis</h4><ul><li>all causes of <a href="/articles/soft-tissue-calcification-2">soft tissue calcification</a>
  • +</li></ul>

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