Calponin

Calponin is an actin-binding protein regulating actin/myosin interaction in smooth muscle and non-muscle cells. It inhibits actin-activated myosin ATPase and stabilizes the actin cytoskeleton. It also serves as a target in immunohistochemistry where it can be used for the identification of myoepithelial cells or the characterization of tumors.

Immunohistochemistry stains might be positive in the following lesions:

Article information

rID: 85178
Section: Pathology
Synonyms or Alternate Spellings:

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