Citation, DOI, disclosures and article data
Citation:
Knipe H, Campos A, Gaillard F, et al. Cardiac sclerosis. Reference article, Radiopaedia.org (Accessed on 22 Mar 2025) https://doi.org/10.53347/rID-42149
Disclosures:
At the time the article was last revised Henry Knipe had the following disclosures:
- Micro-X Ltd, Shareholder (past)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Henry Knipe's current disclosures
Cardiac sclerosis or cardiac cirrhosis is the end-point of passive hepatic congestion from heart failure.
Fibrosis bridging between central zonal regions can occur if passive hepatic congestion persists for a long time. This process is best termed cardiac sclerosis, as unlike in cirrhosis, due to noxious or viral insults, there is minimal nodular regeneration ref.
Aetiology
Causes of cardiac cirrhosis include 1:
ischaemic heart disease: ~30%
cardiomyopathy: ~25%
valvular heart disease: ~25%
restrictive lung disease: ~15%
pericardial disease: ~10%
Features are those of cirrhosis, identical to other causes 3.
Treatment and prognosis
Cardiac cirrhosis may be irreversible even after treatment of the underlying cardiac failure 2.
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1. Thomas D. Boyer, Michael Peter Manns, Arun J. Sanyal et al. Zakim and Boyer's Hepatology. (2012) ISBN: 9781437708813 - Google Books
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2. Torabi M, Hosseinzadeh K, Federle M. CT of Nonneoplastic Hepatic Vascular and Perfusion Disorders. Radiographics. 2008;28(7):1967-82. doi:10.1148/rg.287085067 - Pubmed
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3. Richard M. Gore, Marc S. Levine. Textbook of Gastrointestinal Radiology E-Book. (2014) ISBN: 9780323278119 - Google Books
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