- often multiple
- seen in two-thirds of patients with Carney complex
- skin pigmentation (blue naevi): especially of the face, trunk, lips, and sclera
Multiple other features are also well recognised including:
- extracardiac myxoma
- adrenal gland: primary pigmented nodular adrenocortical disease (PPNAD)
- pituitary adenoma
- psammomatous melanotic schwannoma
- Sertoli cell tumours: most common
Carney complex is due to a mutation of the PRKAR1A gene on the long arm of chromosome 17 (17q) 5.
One way to remember the differentiation between the Carney triad and the Carney complex is that the Carney Complex has Cardiac findings (myxoma).
- 1. Weissleder R, Wittenberg J, Harisinghani MG et-al. Primer of diagnostic imaging. Mosby Inc. (2007) ISBN:0323040683. Read it at Google Books - Find it at Amazon
- 2. Schoepf UJ. CT of the heart, principles and applications. Springer. (2005) ISBN:1592598188. Read it at Google Books - Find it at Amazon
- 3. Carney Complex by Craig T Basson from emedicine.com. Carney Complex
- 4. Grebenc ML, Rosado de christenson ML, Burke AP et-al. Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation. Radiographics. 20 (4): 1073-103. Radiographics (full text) - Pubmed citation
- 5. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK "WHO Classification of Tumours of the Central Nervous System. 4th Edition Revised" ISBN: 9789283244929