Carney triad

Last revised by Rohit Sharma on 31 Dec 2023

Carney triad is a rare syndrome defined by the coexistence of three tumors:

In most cases, only two of the three tumors are present at the time of diagnosis, with the most common combination being GIST and pulmonary chondromas. Although not considered part of the triad, there is an increased incidence of adrenocortical adenoma, pheochromocytoma, and esophageal leiomyoma 6. It typically affects young people, with a female predilection 6. No underlying genetic mutation has been identified 6.


It is not to be confused with the related Carney-Stratakis syndrome, or the unrelated Carney complex.

  • memory tip: it may be helpful to associate "T" in GIST with Carney Triad;  "X" in MyXoma can be associated with Carney compleX

History and etymology

First described by J Aidan Carney, an American professor of pathology, and colleagues in 1977 5.

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