Carney triad is a rare syndrome defined by the coexistence of three tumors:
In most cases, only 2 of the 3 tumors are present at the time of diagnosis. It typically affects young people.
Terminology
It is not to be confused with the related Carney-Stratakis syndrome, or the unrelated Carney complex
History and etymology
First described by J Aidan Carney, an American professor of pathology, and colleagues in 1977 5.
- 1. Carney JA. Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma (Carney Triad): natural history, adrenocortical component, and possible familial occurrence. Mayo Clin. Proc. 1999;74 (6): 543-52. doi:10.4065/74.6.543 - Pubmed citation
- 2. Carney JA, Sheps SG, Go VL et-al. The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. N. Engl. J. Med. 1977;296 (26): 1517-8. doi:10.1056/NEJM197706302962609 - Pubmed citation
- 3. Chew F, Banks K. American Journal of Roentgenology. 2006;187 (3_supplement): . doi:10.2214/AJR.06.0521
- 4. Alrashdi I, Bano G, Maher ER, Hodgson SV. Carney triad versus Carney Stratakis syndrome: two cases which illustrate the difficulty in distinguishing between these conditions in individual patients. Familial cancer. 9 (3): 443-7. doi:10.1007/s10689-010-9323-z - Pubmed
- 5. Aidan Carney, J. The triad of gastric epithelioid leiomyosarcoma, functioning extra-adrenal paraganglioma, and pulmonary chondroma. Cancer. 1979;43 (1): 374–382. doi: 10.1002/1097-0142(197901)43:1<374::AID-CNCR2820430152>3.0.CO;2-T
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