Cenani-Lenz syndactyly (CLS) is a very syndrome primarily characterised by:
- syndactyly/oligodactly: syndactyly is often complete and gives a spoon hand type appearance
- radio-ulnar synostoses
It carries an autosomal recessive inheritance.
It was first described by Asim Cenani, a Turkish medical geneticist and Widukind Lenz, a German medical geneticist in 1967 2.
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- 2. Cenani A, Lenz W. [Total syndactylia and total radioulnar synostosis in 2 brothers. A contribution on the genetics of syndactylia]. Z Kinderheilkd. 1967;101 (3): 181-90. - Pubmed citation
- 3. Pfeiffer RA, Meisel-stosiek M. Present nosology of the Cenani-Lenz type of syndactyly. Clin. Genet. 1982;21 (1): 74-9. - Pubmed citation
- 4. Elçioglu N, Atasu M, Cenani A. Dermatoglyphics in patients with Cenani-Lenz type syndactyly: studies in a new case. Am. J. Med. Genet. 1997;70 (4): 341-5. Am. J. Med. Genet. (link) - Pubmed citation
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