Centrilobular lung nodules
Updates to Article Attributes
Centrilobular lung nodules refer to an HRCT chest imaging descriptor for small 5-10 mm lung nodules which are anatomically located centrally within secondary pulmonary lobules. The term is applied on the basis of positionlocation of the nodule and not its morphology -that is they may be well defined or poorly defined ground glass in appearance.
Pathology
Aetiology
Centrilobular nodules can be observed in a wide variety of lung pathology. They are usually seen with a bronchiolitis (i.e with bronchiolar or peri-bronchiolar abnormalities). Specific conditions include:
- bronchiolitides
- infection with endobronchial spread
- airway spread of tuberculosis
- airway spread of non tuberculous mycobacterial infection
- airway invasive aspergillosis 3
- bronchoalveolar carcinoma with airway spread
- subacute hypersensitivity pneumonitis 1
- respiratory bronchiolitis interstitial lung disease (RB-ILD) 5
- pulmonary vasculitides
When centrilobular nodules are interspersed with linear and branching densities, it is then termed a tree-in-bud pattern.
Radiographic features
HRCT chest
Centrilobular nodules are typically around the small airways and spare the subpleural surfaces. They are typically at least 5-10 mm away from the pleural surfaces ref.
Small pulmonary nodules: HRCT chest approach
See also
-<p><strong>Centrilobular lung nodules </strong>refer to an <a title="HRCT chest" href="/articles/hrct-chest">HRCT chest</a> imaging descriptor for lung nodules which are anatomically located centrally within <a title="Secondary pulmonary lobules" href="/articles/secondary-pulmonary-lobule">secondary pulmonary lobules</a>. The term is applied on the basis of position of the nodule and not its morphology - they may be well defined or poorly defined.</p><h4>Pathology</h4><h5>Aetiology</h5><p>Centrilobular nodules can be observed in a wide variety of lung pathology. They are usually seen with a <a href="/articles/bronchiolitis">bronchiolitis</a> (i.e with bronchiolar or peri-bronchiolar abnormalities). Specific conditions include:</p><ul>- +<p><strong>Centrilobular lung nodules </strong>refer to an <a href="/articles/hrct-chest">HRCT chest</a> imaging descriptor for small 5-10 mm lung nodules which are anatomically located centrally within <a href="/articles/secondary-pulmonary-lobule">secondary pulmonary lobules</a>. The term is applied on the basis of location of the nodule and not its morphology that is they may be well defined or poorly defined ground glass in appearance.</p><h4>Pathology</h4><h5>Aetiology</h5><p>Centrilobular nodules can be observed in a wide variety of lung pathology. They are usually seen with a <a href="/articles/bronchiolitis">bronchiolitis</a> (i.e with bronchiolar or peri-bronchiolar abnormalities). Specific conditions include:</p><ul>
-</ul><p>When centrilobular nodules are interspersed with linear and branching densities, it is then termed a <a href="/articles/tree-in-bud-sign-3">tree-in-bud pattern</a>. </p><h4>Radiographic features</h4><h5>HRCT chest</h5><p>Centrilobular nodules are typically around the small airways and spare the subpleural surfaces. They are typically at least 5-10 mm away from the pleural surfaces <sup>ref</sup>.</p><h4>See also</h4><ul>- +</ul><p>When centrilobular nodules are interspersed with linear and branching densities, it is then termed a <a href="/articles/tree-in-bud-sign-3">tree-in-bud pattern</a>. </p><h4>Radiographic features</h4><h5>HRCT chest</h5><p>Centrilobular nodules are typically around the small airways and spare the subpleural surfaces. They are typically at least 5-10 mm away from the pleural surfaces <sup>ref</sup>.</p><p><a href="/articles/small-pulmonary-nodules-hrct-chest-approach">Small pulmonary nodules: HRCT chest approach </a></p><h4>See also</h4><ul>