Staging of cervical cancer can either be based on the TNM or FIGO system.
Revised FIGO staging of cervical carcinoma 2009 8
- stage 0: cervical intraepithelial neoplasia (HSIL or CIN III)
stage I: confined to cervix
stage Ia: invasive carcinoma only diagnosed by microscopy.
- Ia1: stromal invasion <3 mm in depth and <7 mm in extension (microinvasive)
- Ia2: stromal invasion >3 mm depth and not >5 mm and extension <7 mm
stage Ib: clinically visible lesions limited to the cervix or pre-clinical cancers >stage 1a
- Ib1: clinically visible tumor <4 cm in greatest dimension
- Ib2: clinically visible tumor >4 cm in greatest dimension
- stage Ia: invasive carcinoma only diagnosed by microscopy.
stage II: beyond cervix though not to the pelvic sidewall or lower third of the vagina.
stage IIa: involves upper 2/3rd of vagina without parametrial invasion
- stage IIa1: clinically visible tumor <4 cm in greatest dimension
- stage IIa2: clinically visible tumor >4 cm in greatest dimension
- stage IIb: with parametrial invasion
- stage IIa: involves upper 2/3rd of vagina without parametrial invasion
- stage IIIa: tumor involves the lower third of the vagina with no extension to pelvic sidewall
- stage IIIb: extension to pelvic side wall or causing obstructive uropathy, MR imaging findings that are suggestive of pelvic sidewall involvement include tumor within 3 mm of or abutment of the internal obturator, levator ani, and pyriform muscles and the iliac vessel 6
stage IV: extension beyond true pelvis or biopsy proven to involve the mucosa of the bladder or the rectum
- stage IVa: extension beyond true pelvis or rectal/bladder invasion
- stage IVb: distant organ spread
For an imaging pathway on the best modalities in accurate staging of cervical cancer: see reference 9.
Primary Tumor (T)
- Tx: Primary tumor cannot be assessed
- T0: No evidence of primary tumor
- Tis: Carcinoma in situ
- T1: Cervical carcinoma confined to the uterus
- T1a: Invasive carcinoma diagnosed only by microscopy
- T1b: Clinically visible lesion confined to the cervix
- T2: Cervical carcinoma invades beyond uterus but not to pelvic wall or to lower third of vagina
- T2A: Tumor without parametrial invasion
- T2B: Tumor with parametrial invasion
- T3: Tumor extends to pelvic wall and/or involves lower third of vagina, and/or causes hydronephrosis
- T3a: Tumor involves lower third of vagina, no extension to pelvic wall
- T3b: Tumor extends to pelvic wall and/or causes hydronephrosis
- T4: Tumor invades bladder or rectum, and/or extends beyond true pelvis
Regional Lymph nodes (N)
Nx: Regional lymph nodes cannot be assessed.
No: No regional lymph nodes metastatsis
N1: Regional lymph node metastases
Distant Metastasis (M)
M0: No distant mets
M1: Distant mets (including peritoneal spread, involvement of supraclavicular, mediastinal or para-aortic lymph nodes, lung, liver or bone).
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- 9. Government of Western Australia: Staging of cervical cancer Diagnostic imaging pathway
- 10. American Joint Committee on Cancer - Cervix Uteri Cancer Staging