Chain of lakes sign
Citation, DOI & article data
The chain of lakes sign is a radiological finding describing the appearance of the pancreatic ducts in cases of chronic pancreatitis. Due to repeated inflammation, fibrosis occurs and results in damage and atrophy of the pancreatic tissue as well as dilatation and beading of the main pancreatic duct. In case of additional dilatation of the side branches of the pancreatic duct, the image resembles a chain of lakes "dilated side branches" emanating from the main tributary "dilated main pancreatic duct".
History and etymology
The first mention of the chain of lakes sign in the literature is unclear, although it was clearly well-established when mentioned in an article from 1973 4.
- 1. Schroeder J, Schroeder DR, Schroeder HB, Schroeder. The "chain of lakes" sign. (2018) Abdominal radiology (New York). doi:10.1007/s00261-017-1369-z - Pubmed
- 2. Halefoglu AM. Magnetic resonance cholangiopancreatography: a useful tool in the evaluation of pancreatic and biliary disorders. (2007) World journal of gastroenterology. 13 (18): 2529-34. doi:10.3748/wjg.v13.i18.2529 - Pubmed
- 3. Takahashi M, Pour P. The results of pancreatography during pancreatic carcinogenesis. (1978) The American journal of pathology. 91 (1): 57-70. Pubmed
- 4. Barnes AJ. Idiopathic pancreatic duct dilatation. (1973) Proceedings of the Royal Society of Medicine. 66 (1 Pt 1): 10-1. Pubmed