Cheerio sign (pulmonary nodule)

Cheerio sign in thoracic imaging relates to pulmonary nodules with a central lucent cavity as seen on CT. It is due to proliferation of (malignant or non-malignant) cells around an airway. They are so named because of their resemblance to the breakfast cereal, Cheerios 1-2

The Cheerio sign (pulmonary nodule) may be due to 2

  • lung adenocarcinoma (malignant)
  • pulmonary Langerhans cell histiocytosis (non-malignant)
  • pulmonary meningothelial-like nodules (non-malignant, rare)

Cavitating lung nodules are a differential diagnosis for the Cheerio sign 2

See also 

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Article information

rID: 24406
System: Chest
Section: Signs
Synonyms or Alternate Spellings:
  • Cheerios sign
  • Cheerio sign - lung nodule

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    Figure 1: photograph - cheerios
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