Chemical shift ratio
Last revised by Brian Gilcrease-Garcia ◉
on 25 Jan 2019
Citation, DOI, disclosures and article data
Citation:
Knipe H, Gilcrease-Garcia B, Chemical shift ratio. Reference article, Radiopaedia.org (Accessed on 15 Mar 2025) https://doi.org/10.53347/rID-65806
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rID:
65806
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Disclosures:
At the time the article was created Henry Knipe had no recorded disclosures.
View Henry Knipe's current disclosures
Last revised:
25 Jan 2019,
Brian Gilcrease-Garcia ◉
Disclosures:
At the time the article was last revised Brian Gilcrease-Garcia had no recorded disclosures.
View Brian Gilcrease-Garcia's current disclosures
Revisions:
2 times, by
2 contributors -
see full revision history and disclosures
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Synonyms:
- Chemical shift ratio (CSR)
Calculating the chemical shift ratio (CSR) is one way of differentiating benign thymic tissue from thymic neoplasms 1:
- CSR = (tSIopp / mSIopp) / (tSIin / mSIin)
in = in phase, m = muscle, opp = opposed phase, SI = signal intensity, and t = thymus
Using a cut-off if 0.849, CSR is 100% specific and ~97% sensitive for the diagnosis of residual thymus / thymic hyperplasia 2.
References
- 1. Shetty AS, Sipe AL, Zulfiqar M, Tsai R, Raptis DA, Raptis CA, Bhalla S. In-Phase and Opposed-Phase Imaging: Applications of Chemical Shift and Magnetic Susceptibility in the Chest and Abdomen. (2019) Radiographics : a review publication of the Radiological Society of North America, Inc. 39 (1): 115-135. doi:10.1148/rg.2019180043 - Pubmed
- 2. Priola AM, Priola SM, Ciccone G, Evangelista A, Cataldi A, Gned D, Pazè F, Ducco L, Moretti F, Brundu M, Veltri A. Differentiation of rebound and lymphoid thymic hyperplasia from anterior mediastinal tumors with dual-echo chemical-shift MR imaging in adulthood: reliability of the chemical-shift ratio and signal intensity index. (2015) Radiology. 274 (1): 238-49. doi:10.1148/radiol.14132665 - Pubmed
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