Choline peak

Dr Henry Knipe and A.Prof Frank Gaillard et al.

Choline is a precursor of acetylcholine (ACH), a component of cell membranes which is commonly examined in MR spectroscopy. It resonates at 3.2 ppm chemical shift.

It is a marker of cellular membrane turnover and therefore elevated in neoplasms, demyelination and gliosis. In the setting of gliomas, elevated choline beyond the margins of contrast enhancement is suggestive of further extension of the neoplastic cells.

MR spectroscopy
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Article information

rID: 27823
Section: Physics
Tag: refs
Synonyms or Alternate Spellings:

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