Choline peak

Dr Dan J Bell and A.Prof Frank Gaillard et al.

Choline is a precursor of acetylcholine (ACH), a component of cell membranes which is commonly examined in MR spectroscopy. It resonates at 3.2 ppm chemical shift.

It is a marker of cellular membrane turnover and therefore elevated in neoplasms, demyelination and gliosis. In the setting of gliomas, elevated choline beyond the margins of contrast enhancement is suggestive of further extension of the neoplastic cells.

MR spectroscopy
Share article

Article information

rID: 27823
Tag: refs
Synonyms or Alternate Spellings:

Support Radiopaedia and see fewer ads

Cases and figures

  • Drag
    Case 1: low-grade glioma
    Drag here to reorder.
  • Drag
    MR Spectroscopy -...
    Case 2: primary CNS lymphoma
    Drag here to reorder.
  • Updating… Please wait.

    Alert accept

    Error Unable to process the form. Check for errors and try again.

    Alert accept Thank you for updating your details.