Although frequently used as a synonym for calcium pyrophosphate dihydrate deposition disease (CPPD), chondrocalcinosis simply means visible calcification of both hyaline cartilage and fibrocartilage.
It has a reported prevalence of 5-15% 2 and is thought to increase with age.
Occurs due deposition of calcium crystals which can consist of 2:
- calcium pyrophosphate dihydrate: most common
- dicalcium phosphate dihydrate
- calcium hydroxyapatite
Calcium pyrophosphate dihydrate deposition disease (CPPD) is a very common cause of chondrocalcinosis. However, there are many more, including:
- hypercalcaemia, especially hyperparathyroidism
- Wilson disease
- trauma: focal chondrocalcinosis in a traumatised joint
See Chondrocalcinosis (mnemonic) article for three useful mnemonics.
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