Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Alhusseiny K, Abuhashem N, et al. Chorionic bump. Reference article, Radiopaedia.org (Accessed on 21 Jan 2025) https://doi.org/10.53347/rID-29910
Chorionic bump is a finding that can be uncommonly seen in a first-trimester scan. It may represent a small hematoma bulging into the gestational sac or an anembryonic (failed) second pregnancy that is being resorbed. It is also seen in some patients undergoing infertility treatment.
It is an uncommon sign, seen in about 0.4-0.7% of pregnancies <10 weeks 1,9.
A chorionic bump represents an arterial hematoma in the chorionic plate.
Ultrasound
irregular, convex soft tissue bulge projecting from the choriodecidual surface into the gestational sac
isoechoic to chorion
avascular on Doppler mapping
MRI
Treatment and prognosis
A chorionic bump has been associated with a guarded prognosis for early pregnancy where the rate of miscarriage has been considered twice the normal rate 2.
Studies have suggested 62-65% overall live birth rate (83% if no other abnormalities) 5,7, but some have suggested that the risk may be overestimated 7. All pregnancies with multiple chorionic bumps ended in demise (100%) 5.
A chorionic bump can occasionally progress to a subamniotic hematoma from the second trimester onwards 10.
There is one case report of an association with neural tube defects (acrania) 6 which could be related to decreased folate levels.
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1. Harris RD, Couto C, Karpovsky C et-al. The chorionic bump: a first-trimester pregnancy sonographic finding associated with a guarded prognosis. J Ultrasound Med. 2006;25 (6): 757-63. J Ultrasound Med (full text) - Pubmed citation
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2. Sana Y, Appiah A, Davison A et-al. Clinical significance of first-trimester chorionic bumps: a matched case-control study. Ultrasound Obstet Gynecol. 2013;42 (5): 585-9. doi:10.1002/uog.12528 - Pubmed citation
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3. Tan S, Ipek A, Akın Sivaslıoğlu A et-al. The chorionic bump: Radiologic and pathologic correlation. J Clin Ultrasound. 2011;39 (1): 35-7. doi:10.1002/jcu.20755 - Pubmed citation
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4. Northrup BE, Harris RD. The chorionic bump in an ectopic pregnancy. J Clin Ultrasound. 2009;37 (5): 292-4. doi:10.1002/jcu.20544 - Pubmed citation
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5. Arleo EK, Troiano RN. Chorionic bump on first-trimester sonography: not necessarily a poor prognostic indicator for pregnancy. J Ultrasound Med. 2014;34 (1): 137-42. doi:10.7863/ultra.34.1.137 - Pubmed citation
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6. Wegrzyn P, Brawura-Biskupski-Samaha R, Borowski D et-al. The chorionic bump associated with acrania-case report. Ginekol. Pol. 2014;84 (12): 1055-8. Pubmed citation
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7. Arleo EK, Dunning A, Troiano RN. Chorionic Bump in Pregnant Patients and Associated Live Birth Rate: A Systematic Review and Meta-analysis. J Ultrasound Med. 2015;34 (4): 553-7. doi:10.7863/ultra.34.4.553 - Pubmed citation
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8. Yousaf A, Tayyab A, Anil M, Ahmed M, Ahmed S, Alobadli A. Chorionic Bump: Radiologic Features and Pregnancy Outcomes. Cureus. 2020;12(11):e11480. doi:10.7759/cureus.11480 - Pubmed
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9. McCarter K, Willson S, Shah N, Pereira N. Chorionic Bump in Early Pregnancy Associated with First-Trimester Miscarriage. BMJ Case Rep. 2020;13(7):e236624. doi:10.1136/bcr-2020-236624 - Pubmed
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10. Galleguillos C & Sepulveda W. Chorionic Bump: Progression to a Subamniotic Hematoma. Ultrasound. 2021;30(1):90-3. doi:10.1177/1742271x211008565
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