Choroid plexus lipomas are uncommon and like other intracranial lipomas are usually found incidentally at the trigones of the lateral ventricles when imaging is obtained for other indications.
Some of the literature refers to the extension of tubulonodular pericallosal lipoma into the choroid plexus within the bodies of the lateral ventricles as choroid plexus lipomas 6. Although this too is adipose tissue within the choroid plexus, it is distinct from small isolated lipomas in the choroid at the trigones of the lateral ventricles.
In one study the prevalence of choroid plexus lipomas was found to be 0.45% 1. They can occur in all age groups.
Most patients are asymptomatic with the lesion being discovered incidentally 3.
Choroid plexus lipomas are not true neoplasms but are rather a form of congenital malformation due to the persistence of the meninx primitiva 4. The lesions are typically solitary although may be bilateral in some cases.
Transcranial antenatal ultrasound may reveal a well defined hyperechoic mass 5.
Choroid plexus lipomas may be found on CT. However, CT has been noted to have poor sensitivity for their detection presumably due to narrow window (brain window) setting of routine brain CT 1,2
MRI is much more sensitive for detecting choroid plexus lipomas. They are usually small rounded lesions between 2 mm to 1 cm in diameter located in the region of trigone of the lateral ventricle 3. They follow fat on all sequences and therefore have the following sequence characteristics 1-3:
- T1: high signal
- T1 C+ (Gd): non-enhancing
- T2: high signal
- fat saturation: lose signal
May exhibit chemical shift artefact.
Treatment and prognosis
These lesions are invariably asymptomatic and treatment is generally not required.
- 1. Uchino A, Hasuo K, Matsumoto S, Masuda K. Solitary choroid plexus lipomas: CT and MR appearance. (1993) AJNR. American journal of neuroradiology. 14 (1): 116-8. Pubmed
- 2. Mahajan PS, Al Moosawi NM, Hasan IA. A Rare Case of Pericallosal Lipoma Associated with Bilaterally Symmetrical Lateral Ventricular Choroid Plexus Lipomas without Corpus Callosal Anomalies. (2013) Journal of clinical imaging science. 3: 69. doi:10.4103/2156-7514.124109 - Pubmed 1.
- 3. Sener RN. Isolated choroid plexus lipomas. (1995) Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 19 (5): 423-6. Pubmed
- 4. Truwit CL, Barkovich AJ. Pathogenesis of intracranial lipoma: an MR study in 42 patients. (1990) AJR. American journal of roentgenology. 155 (4): 855-64; discussion 865. doi:10.2214/ajr.155.4.2119122 - Pubmed
- 5. Naeini RM, Yoo JH, Hunter JV. Spectrum of choroid plexus lesions in children. (2009) AJR. American journal of roentgenology. 192 (1): 32-40. doi:10.2214/ajr.192.5_supplement.0a32 - Pubmed
- 6. Truwit CL, Williams RG, Armstrong EA, Marlin AE. MR imaging of choroid plexus lipomas. (1990) AJNR. American journal of neuroradiology. 11 (1): 202-4. Pubmed