Chronic epididymitis

Last revised by Subhan Iqbal on 4 Oct 2021

Chronic epididymitis is a clinical diagnosis based on chronic epididymal pain lasting for at least six weeks 8. It is a common, possibly the most common, cause of scrotal pain. 

One study found the median age at presentation is 46-49 years with an average duration of symptoms prior to presentation of ~5 years 1,6

Patients present with chronic point tenderness of their epididymis +/- a palpable mass or swelling 1,2,8

One classification of chronic epididymis is 1-4:

Ultrasound may be normal in a large number of patients. When abnormal, findings of epididymitis, epididymal cyst, or epididymal mass may be present 7

Initial treatment consists of a trial of antibiotics as well as scrotal support, anti-inflammatories, and analgesia including nerve blocks. Chronic epididymitis is generally considered "self-limited" albeit with a chronic course; refractory cases may require surgical resection of the epididymis 5

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