Chronic invasive fungal sinusitis

Chronic invasive fungal sinusitis (CIFS) is a form of invasive fungal sinusitis

The condition has a more prolonged course than acute invasive fungal sinusitis, usually more than 12 weeks 5. Patients are usually immunocompetent or have a milder level of immunocompromise. There may be a history of chronic sinusitis.

CT usually shows homogeneous opacification (iso- to hyperattenuating to muscle tissue) of the affected sinus(es).

Other suggestive features include:

  • relative lack of expansion of sinuses 2
  • mottled lucencies or irregular bone destruction may be seen
  • bone erosion being localised to the area of extra-sinus extension 2
  • extra-sinus component of the disease being more than the intra-sinus component 2
  • there may also be sclerotic changes in the bony walls of the affected sinuses representing chronicity of disease 3

Signal characteristics of affected region include:

  • T1: iso- or hypointense signal
  • T2: usually markedly hypointense signal
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Article information

rID: 37226
System: Head & Neck
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Chronic invasive fungal sinus infection
  • Indolent invasive fungal sinusitis
  • Chronic invasive fungal sinusitis (CIFS)

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Cases and figures

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    Case 1
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    Case 2: cerebral invasion
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    Case 3
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