Circumferential resection margin
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At the time the article was created Matt A. Morgan had no recorded disclosures.View Matt A. Morgan's current disclosures
At the time the article was last revised Vikas Shah had no recorded disclosures.View Vikas Shah's current disclosures
Circumferential resection margin (CRM) is a term used to denote the standard plane of excision of total mesorectal excision, used for resection of rectal cancers. The anatomic correlate is the mesorectal fascia. The distance between tumor tissue or satellite tumor deposits and the mesorectal fascia, as judged at staging MRI, is predictive of involvement of the CRM and likelihood of incomplete resection at surgery, and hence has long term prognostic implications. Note that the mesorectal fascia is only considered the CRM for the non-peritonealised portion of the rectum.
Pathologic evaluation of the resection margin on the excised rectum has been considered important for determining the risk of local recurrence. A margin of ≤1 mm is considered by some to be a negative prognostic factor for local recurrence 2.
The prognostic value of the circumferential resection margin has been called into question in some recent studies 3.
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