Claude syndrome
Last revised by Daniel J Bell on 9 Mar 2018
Citation, DOI, disclosures and article data
Citation:
Abdrabou A, Bell D, Sharma R, et al. Claude syndrome. Reference article, Radiopaedia.org (Accessed on 10 Oct 2024) https://doi.org/10.53347/rID-32267
Permalink:
rID:
32267
Article created:
22 Nov 2014,
Ahmed Abdrabou
Disclosures:
At the time the article was created Ahmed Abdrabou had no recorded disclosures.
View Ahmed Abdrabou's current disclosures
Last revised:
9 Mar 2018,
Daniel J Bell ◉
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Revisions:
6 times, by
5 contributors -
see full revision history and disclosures
Systems:
Sections:
Synonyms:
- Claude's syndrome
Claude syndrome is one of the brainstem stroke syndromes in which there is infarction of the dorsomedial aspect of the midbrain.
On this page:
Clinical presentation
Clinical picture is characteristic and includes ipsilateral oculomotor nerve palsy and contralateral upper and lower limb ataxia 1-4.
Pathology
Claude syndrome is generally caused by an ischemic stroke secondary to occlusion of the small perforating branches of the posterior cerebral artery supplying the dorsomedial aspect of the midbrain 1-4. The infarction involves the medial aspect of the red nucleus with the rubrodentate fibers, CN III nucleus and superior cerebellar peduncle 1-4.
History and etymology
The syndrome was first described by Henri Claude (1869-1945), a French neurologist, in 1912 5.
References
- 1. Seo SW, Heo JH, Lee KY, Shin WC, Chang DI, Kim SM, Heo K. Localization of Claude's syndrome. Neurology. 57 (12): 2304-7. Pubmed
- 2. Fong CS. Claude's syndrome associated with supranuclear horizontal gaze palsy caused by dorsomedial midbrain infarction. Acta Neurol Taiwan. 2005;14 (3): 147-50. Pubmed citation
- 3. Ropper AH, Samuels MA, Klein JP. Adams and Victor's principles of neurology 10th ed. New York: McGraw-Hill Medical Pub. Division; 2014.
- 4. Liu GT, Crenner CW, Logigian EL, Charness ME, Samuels MA. Midbrain syndromes of Benedikt, Claude, and Nothnagel: setting the record straight. Neurology. 42 (9): 1820-2. Pubmed
- 5. Claude H. Syndrome pedonculaire de la region du noyau rouge. Rev Neurol (Paris) 1912;1(23):311-313.
Incoming Links
Related articles: Stroke and intracranial haemorrhage
-
stroke and intracranial hemorrhage
- general articles
-
ischemic stroke
- general discussions
- scoring and classification systems
- Alberta stroke program early CT score (ASPECTS)
- ASCOD classification
- Canadian Neurological Scale
- Heidelberg bleeding classification
- NIH Stroke Scale
- Mathew stroke scale
- modified Rankin scale
- Orgogozo Stroke Scale
- Scandinavian Stroke Scale
- thrombolysis in cerebral infarction (TICI) scale
- TOAST classification
- collateral vessel scores
- signs
- by region
- hemispheric infarcts
- frontal lobe infarct
- parietal lobe infarct
- temporal lobe infarct
- occipital lobe infarct
- alexia without agraphia syndrome: PCA
- cortical blindness syndrome (Anton syndrome): top of basilar or bilateral PCA
- Balint syndrome: bilateral PCA
- lacunar infarct
-
thalamic infarct
- artery of Percheron infarct
- Déjerine-Roussy syndrome (thalamic pain syndrome): thalamoperforators of PCA
- top of the basilar syndrome
- striatocapsular infarct
- choroid plexus infarct
- cerebellar infarct
-
brainstem infarct
- midbrain infarct
- Benedikt syndrome: PCA
- Claude syndrome: PCA
- Nothnagel syndrome: PCA
- Weber syndrome: PCA
- Wernekink commissure syndrome
- pontine infarct
- Brissaud-Sicard syndrome
- facial colliculus syndrome
- Gasperini syndrome: basilar artery or AICA
- inferior medial pontine syndrome (Foville syndrome): basilar artery
- lateral pontine syndrome (Marie-Foix syndrome): basilar artery or AICA
- locked-in syndrome: basilar artery
- Millard-Gubler syndrome: basilar artery
- Raymond syndrome: basilar artery
- medullary infarct
- Babinski-Nageotte syndrome
- Cestan-Chenais syndrome
- hemimedullary syndrome (Reinhold syndrome)
- lateral medullary stroke syndrome (Wallenberg syndrome)
- medial medullary syndrome (Déjerine syndrome)
- Opalski syndrome
- midbrain infarct
- acute spinal cord ischemia syndrome
- hemispheric infarcts
- by vascular territory
- by vessel size
- treatment options
- complications
-
intracranial hemorrhage
-
intra-axial hemorrhage
- signs and formulas
- ABC/2 (volume estimation)
- black hole sign
- blend sign
- cashew nut sign
- CTA spot sign
- island sign
- satellite sign
- swirl sign
- zebra sign
- by type
- by location
- signs and formulas
- extra-axial hemorrhage
- extradural hemorrhage (EDH)
- intralaminar dural hemorrhage
- subdural hemorrhage (SDH)
-
subarachnoid hemorrhage (SAH)
- types
- complications
- grading systems
- subpial hemorrhage
-
intra-axial hemorrhage
Unable to process the form. Check for errors and try again.