Claude syndrome
Claude syndrome is one of the brainstem stroke syndromes in which there is infarction of the dorsomedial aspect of the midbrain.
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Clinical presentation
Clinical picture is characteristic and includes ipsilateral oculomotor nerve palsy and contralateral upper and lower limb ataxia 1-4.
Pathology
Claude syndrome is generally caused by an ischemic stroke secondary to occlusion of the small perforating branches of the posterior cerebral artery supplying the dorsomedial aspect of the midbrain 1-4. The infarction involves the medial aspect of the red nucleus with the rubrodentate fibers, CN III nucleus and superior cerebellar peduncle 1-4.
History and etymology
The syndrome was first described by Henri Claude (1869-1945), a French neurologist, in 1912 5.
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ischemic stroke
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brainstem infarct
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- medullary infarct
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- hemimedullary syndrome (Reinhold syndrome)
- lateral medullary stroke syndrome (Wallenberg syndrome)
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intracranial hemorrhage
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intra-axial hemorrhage
- signs
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- extra-axial hemorrhage
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intra-axial hemorrhage
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ischemic stroke
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