Clear cell carcinoma of the endometrium
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Yap J, Goel A, et al. Clear cell carcinoma of the endometrium. Reference article, Radiopaedia.org (Accessed on 17 Mar 2025) https://doi.org/10.53347/rID-17251
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rID:
17251
Article created:
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Joshua Yap had no financial relationships to ineligible companies to disclose.
View Joshua Yap's current disclosures
Revisions:
3 times, by
3 contributors -
see full revision history and disclosures
Systems:
Synonyms:
- Clear cell carcinoma of the uterus
- Clear cell carcinoma of uterus
- CCC uterus
- Clear cell carcinoma of the endometrium
- CCC endometrium
- Clear cell carcinoma of endometrium
- Clear cell carcinoma (CCC) of endometrium
- Endometrial clear cell carcinoma
- Endometrial clear cell carcinoma (CCC)
- Endometrial clear cell cancer
Clear cell carcinoma (CCC) of the endometrium is an uncommon histological subtype of endometrial cancer, only accounting for 1-5.5% of all endometrial carcinomas. It is often associated with an aggressive clinical behavior and poorer outcome 4,5. Only few case reports have described MRI findings of this subtype which appears as a mixed solid and cystic lesion with eccentric solid components 3.
References
- 1. Petignat P, Usel M, Gauthier P et-al. Outcome of uterine clear cell carcinomas compared to endometrioid carcinomas and poorly-differentiated endometrioid carcinomas. Eur. J. Gynaecol. Oncol. 2008;29 (1): 57-60. - Pubmed citation
- 2. Abeler VM, Vergote IB, Kjørstad KE et-al. Clear cell carcinoma of the endometrium. Prognosis and metastatic pattern. Cancer. 1996;78 (8): 1740-7. - Pubmed citation
- 3. Hiromura T, Tanaka YO, Nishioka T et-al. Clear cell adenocarcinoma of the uterine cervix arising from a background of cervical endometriosis. Br J Radiol. 2009;82 (973): e20-2. doi:10.1259/bjr/75304693 - Pubmed citation
- 4. Gadducci A, Cosio S, Spirito N et-al. Clear cell carcinoma of the endometrium: a biological and clinical enigma. Anticancer Res. 2010;30 (4): 1327-34. Anticancer Res. (link) - Pubmed citation
- 5. Malpica A, Tornos C, Burke TW et-al. Low-stage clear-cell carcinoma of the endometrium. Am. J. Surg. Pathol. 1995;19 (7): 769-74. - Pubmed citation
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