Colloid nodule (thyroid)

Last revised by Dr Joshua Yap on 10 Oct 2022

Colloid nodules are non-neoplastic benign nodules occurring within the thyroid gland. They form the vast majority of nodular thyroid disease.

Pathology

Colloid nodules are composed of irregularly enlarged follicles containing abundant colloid. A colloid nodule may be single or multiple and can vary considerably in size.

Some colloid nodules can be cystic (cystic colloid nodule) and may contain areas of necrosis, hemorrhage and/or calcification. 

Calcification may represent prior multinodular goiter hemorrhage.

Radiographic features

Plain radiograph
  • calcification in the thyroid secondary to prior hemorrhage

  • tracheal deviation

Ultrasound

ADVERTISEMENT: Supporters see fewer/no ads

Cases and figures

  • Case 1
    Drag here to reorder.
  • Case 2: with cystic degeneration
    Drag here to reorder.
  • Case 3
    Drag here to reorder.
  • Case 4
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.