Columnar alteration with prominent apical snouts and secretions
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Columnar alteration with prominent apical snouts and secretions (CAPSS) is a pathological entity encountered when breast biopsies are done for investigation of punctate or amorphous calcifications. CAPSS involves the terminal ductal and lobular units (TDLU's).
It is sometimes classified under the spectrum of borderline breast disease. Therefore when the histology reveals CAPSS with atypia on a stereotactic or ultrasound guided biopsy, an excisional biopsy is recommended to exclude associated DCIS 4.
- 1. Fraser JL, Raza S, Chorny K et-al. Columnar alteration with prominent apical snouts and secretions: a spectrum of changes frequently present in breast biopsies performed for microcalcifications. Am. J. Surg. Pathol. 1998;22 (12): 1521-7. Am. J. Surg. Pathol. (link) - Pubmed citation
- 2. Guerra-wallace MM, Christensen WN, White RL. A retrospective study of columnar alteration with prominent apical snouts and secretions and the association with cancer. Am. J. Surg. 2004;188 (4): 395-8. doi:10.1016/j.amjsurg.2004.06.037 - Pubmed citation
- 3. Pandey S, Kornstein MJ, Shank W et-al. Columnar cell lesions of the breast: mammographic findings with histopathologic correlation. Radiographics. 2007;27 Suppl 1 : S79-89. doi:10.1148/rg.27si075515 - Pubmed citation
- 4. Cardeñosa G. Clinical breast imaging, a patient focused teaching file. Lippincott Williams & Wilkins. (2006) ISBN:0781762677. Read it at Google Books - Find it at Amazon
- 5. Paredes ES. Atlas of mammography. Lippincott Williams & Wilkins. (2007) ISBN:0781764335. Read it at Google Books - Find it at Amazon