Combined cerebral edema
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At the time the article was created Maxime St-Amant had no recorded disclosures.View Maxime St-Amant's current disclosures
At the time the article was last revised Yahya Baba had no financial relationships to ineligible companies to disclose.View Yahya Baba's current disclosures
Combined cerebral edema is a type of cerebral edema in which there is a mixed pattern of different types of cerebral edema (cytotoxic, vasogenic or osmotic).
It is usually associated with severe systemic damage, such as:
severe sepsis / severe inflammatory condition
intoxication / metabolic systemic disease
The radiographic features are those of both cytotoxic and vasogenic cerebral edema. Hence, both the grey and white matter are affected, with sulci effacement, loss of cortical differentiation and finger-like hypodensities (CT-scan) / hyperintensities (T2/FLAIR).
Treatment and prognosis
This finding usually carries a very poor prognosis.
A cerebral herniation is almost inevitable unless aggressive treatment of the underlying etiology is quickly initiated.
- 1. Ho M, Rojas R, Eisenberg R. Cerebral Edema. AJR Am J Roentgenol. 2012;199(3):W258-73. doi:10.2214/AJR.11.8081 - Pubmed