Combined cerebral edema

Last revised by Yahya Baba on 9 Jan 2023

Combined cerebral edema is a type of cerebral edema in which there is a mixed pattern of different types of cerebral edema (cytotoxic, vasogenic or osmotic).

It is usually associated with severe systemic damage, such as:

Radiographic features

The radiographic features are those of both cytotoxic and vasogenic cerebral edema. Hence, both the grey and white matter are affected, with sulci effacement, loss of cortical differentiation and finger-like hypodensities (CT-scan) / hyperintensities (T2/FLAIR).

Treatment and prognosis

This finding usually carries a very poor prognosis.

A cerebral herniation is almost inevitable unless aggressive treatment of the underlying etiology is quickly initiated.

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Cases and figures

  • Case 1
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