Computed tomography texture analysis

Computed tomography texture analysis (or CTTA) is a method to obtain new useful biomarkers that provide objective and quantitative assessment of tumour heterogeneity by analysing the differences and patterns within the pixel values of an image. CTs can be worked with as a matrix of numbers, corresponding to Hounsfield units. Algorithms that perform mathematical operations on these matrices can reveal patterns and characteristics. There are over twenty texture analysis parameters which are standardized in radiomics

Parameters assessed may include

  1. grey-level frequency distribution: pixel intensity histograms
  2. mean intensity, threshold (percentage of pixels within a specified range)
  3. entropy (irregularity)
  4. standard deviation
  5. skewness (asymmetry)
  6. kurtosis (peakedness/flatness of pixel histogram)

Applications

Oncological applications
  • lesion characterisation
  • pretreatment tumour assessment
  • response evaluation for tumours
Non-oncological applications
Share article

Article information

rID: 56604
System: Oncology
Section: Approach, Physics
Synonyms or Alternate Spellings:
  • CTTA

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.