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Citation:
Neubauer J, Fortin F, Murphy A, Condyle-C1 interval (CCI). Reference article, Radiopaedia.org (Accessed on 26 Mar 2025) https://doi.org/10.53347/rID-66363
The condyle-C1 interval (CCI) is the measurement of the interval between condyle and C1 at four equidistant points on the joint surface in sagittal and coronal reconstructions of computed tomography.
The CCI is reported to have a high lateral symmetry in children 1. Used with a cut-off of 4 mm, the CCI has a high diagnostic accuracy regarding atlanto-occipital dislocation in paediatric patients 2.
Despite this, many cases of atlanto-occipital injury can be missed using this criteria alone. In patients with a mecanism of trauma compatible with this type of injury, MRI evaluation is recommended to evaluate potential ligamentous injury 3.
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1. Pang D, Nemzek WR, Zovickian J. Atlanto-occipital dislocation: part 1--normal occipital condyle-C1 interval in 89 children. (2007) Neurosurgery. 61 (3): 514-21; discussion 521. doi:10.1227/01.NEU.0000290897.77448.1F - Pubmed
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2. Pang D, Nemzek WR, Zovickian J. Atlanto-occipital dislocation--part 2: The clinical use of (occipital) condyle-C1 interval, comparison with other diagnostic methods, and the manifestation, management, and outcome of atlanto-occipital dislocation in children. (2007) Neurosurgery. 61 (5): 995-1015; discussion 1015. doi:10.1227/01.neu.0000303196.87672.78 - Pubmed
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3. B. Corcoran, L.L. Linscott, J.L. Leach, S. Vadivelu. Application of Normative Occipital Condyle-C1 Interval Measurements to Detect Atlanto-Occipital Injury in Children. (2016) American Journal of Neuroradiology. 37 (5): 958. doi:10.3174/ajnr.A4641 - Pubmed
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