Corpora amylacea
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Citation:
Morgan M, Weerakkody Y, Bell D, Corpora amylacea. Reference article, Radiopaedia.org (Accessed on 16 Jan 2025) https://doi.org/10.53347/rID-75939
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75939
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At the time the article was created Matt A. Morgan had no recorded disclosures.
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At the time the article was last revised Yuranga Weerakkody had no recorded disclosures.
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The corpora amylacea ("bodies of starch") are a histologic finding, encountered more frequently in the brain, prostate, lung, and uterus. The corpora amylacea are thought to be sulfated glycosaminoglycans 1. Some have described it as a localized amyloidosis 2.
In the prostate they appear to arise partly from prostatic secretions and may calcify (in the form of hydroxyapatite) 3. After calcification they can become visible on imaging. Inflammation, possibly from bacterial infection, is theorized to be a factor for their formation in the prostate 3.
References
- 1. Cohen RJ, McNeal JE, Redmond SL, Meehan K, Thomas R, Wilce M, Dawkins HJ. Luminal contents of benign and malignant prostatic glands: correspondence to altered secretory mechanisms. (2000) Human pathology. 31 (1): 94-100. doi:10.1016/s0046-8177(00)80204-x - Pubmed
- 2. Cross PA, Bartley CJ, McClure J. Amyloid in prostatic corpora amylacea. (1992) Journal of clinical pathology. 45 (10): 894-7. doi:10.1136/jcp.45.10.894 - Pubmed
- 3. Sfanos KS, Wilson BA, De Marzo AM, Isaacs WB. Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer. (2009) Proceedings of the National Academy of Sciences of the United States of America. 106 (9): 3443-8. doi:10.1073/pnas.0810473106 - Pubmed
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