Corpus callosum impingement syndrome

Corpus callosum impingement syndrome (CCIS) is caused by impingement of the corpus callosal fibers against inferior free margin of the falx cerebri due to longstanding and severe hydrocephalus and stretching of the lateral ventricles. this results in ischaemia and eventually atrophy of the neural fibers in corpus callosum. CCIS does not appear to produce any clinical symptoms but recognition of this is crucial to avoid misinterpretation which can lead to unnecessary intervention. 

Radiographic features


MRI shows severe hydrocephalus and stretching of the lateral ventricles.

Initially, corpus callosum appears swollen with low signal on T1WI and hyperintense on T2/FLAIR sequences. Longstanding changes include hyperintensity of the CC on T2/FAILR as well as volume loss and atrophy which is most pronounced in rostral portion and body of the CC. These findings can persist even after decompression of the ventricles. 

Share article

Article information

rID: 37002
Synonyms or Alternate Spellings:
  • Corpus callosum impingement syndrome (CCIS)

Updating… Please wait.

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.