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Revision 2 for 'COVID-19'

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Novel coronavirus-infected pneumonia

Novel coronavirus-infected pneumonia (NCIP) is an emerging zoonotic illness caused by a novel coronavirus, which has provisionally been called 2019-nCoV. The first cases were seen in Wuhan, China, in December 2019, and have been linked to a live animal market 1,2

Epidemiology

As of January 24th 2020, over 800 cases of novel coronavirus-infected pneumonia have been identified, with a mortality rate of 3% 2.

Clinical presentation

The novel coronavirus primarily presents as a pneumonia, however its full spectrum of clinical effects remains to be determined 1,2.

Pathology

The recently identified 2019-nCoV, is the putative cause of novel coronavirus-infected pneumonia. It is a member of the Betacoronavirus genus, one of the genera of the Coronaviridae family of viruses. Coronaviruses are enveloped single-stranded RNA viruses, that are found in humans, many other mammals and birds. These viruses are responsible for pulmonary, hepatic, CNS and intestinal disease. 

Hitherto, six coronaviruses have been known to be responsible for human diseases, two are zoonoses, the severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), both of which may sometimes be fatal. The remaining four viruses are widespread in human society and cause mild coryzal illnesses. 

Radiographic features

Primary findings on chest radiograph and CT are those of a pneumonia.

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