Crossed cerebellar diaschisis

Crossed cerebellar diaschisis (CCD) refers to a depression of blood flow and metabolism affecting the cerebellar hemisphere occurring as a result of a contralateral focal, supratentorial lesion (e.g. infarct, radiation necrosis, following tumour resection).

Pathology

It is a well-recognised phenomenon following cerebral infarction. The most likely mechanism is thought to be interruption of cortico-ponto-cerebellar connections due to the infarct which then causes deafferentation and transneural metabolic depression of the contralateral cerebellar hemisphere

Radiographic features

Imaging has to be interpreted in the correct clinical context. 

CT / MRI and CT perfusion

CT perfusion performed during acute stroke may show a contralateral perfusion abnormality in about 20 % of cases 4. CBF and CBV maps show only mild-to-moderate reduction in these parameters, and are never low enough to classify the personal abnormalities as infarcts. There can be volume loss to the contralateral cerebellar hemisphere.

Nuclear medicine

FDG PET shows hypometabolism in affected cerebellar hemisphere 2.

Share Article

Article Information

rID: 11015
Tag: cases
Synonyms or Alternate Spellings:
  • Crossed cerebellar diaschisis (CCD)

Support Radiopaedia and see fewer ads

  • Drag
    Case 1: PET
    Drag here to reorder.
  • Drag
    Disruption of the...
    Case 2
    Drag here to reorder.
  • Updating… Please wait.
    Loadinganimation

    Alert accept

    Error Unable to process the form. Check for errors and try again.

    Alert accept Thank you for updating your details.