Crystal arthropathies are a group of joint disorders due to the deposition of crystals in and around joints which lead to joint destruction and soft tissue masses.
Pathology
The most common crystal arthropathies are:
- gouty arthropathy due to monosodium urate (MSU) deposition
- pseudogout due to calcium pyrophosphate dihydrate (CPPD) deposition
Other less common crystals are 4:
- calcium phosphate hydroxyapatite in generalized peritendonitis, osteoarthritis and erosive arthropathies
- calcium oxalate aluminum phosphate deposited in end-stage renal failure patients on dialysis, short gut syndrome and primary oxalosis
- cholesterol deposited in rheumatoid arthritis and osteoarthritis
- xanthine
- cysteine
- lysophospholipase (Charcot-Leyden)
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