Cumulus oophorus
Last revised by Dennis Odhiambo Agolah
on 6 Aug 2022
Citation, DOI, disclosures and article data
Citation:
Morgan M, Agolah D, Weerakkody Y, et al. Cumulus oophorus. Reference article, Radiopaedia.org (Accessed on 13 Dec 2024) https://doi.org/10.53347/rID-42514
rID:
42514
Article created:
Disclosures:
At the time the article was created Matt A. Morgan had no recorded disclosures.
View Matt A. Morgan's current disclosures
Last revised:
6 Aug 2022,
Dennis Odhiambo Agolah
Disclosures:
At the time the article was last revised Dennis Odhiambo Agolah had no recorded disclosures.
View Dennis Odhiambo Agolah's current disclosures
Revisions:
9 times, by
6 contributors -
see full revision history and disclosures
Systems:
Tags:
Synonyms:
- Ovigerus
- Proligerus disc
- Cumuli oophori
- Proligerus membrane
- Discus proligerus
Cumulus oophorus refers to an appearance in the ovary in which multiple granulosa cells enlarge around a developing oocyte. These support cells ("cumulus cells") serve multiple functions in the maturation of the oocyte. They may occasionally be seen during a pelvic ultrasound, and should not be confused with a pathological finding.
60-65% of the time a cumulus oophorus is visualized 12-24 hours before ovulation 3.
It comprises a collection of the cells in a mature follicle that protrude into the cavity of the follicle. It is a sign of imminent ovulation, but its absence has little significance in predicting the maturity of the oocyte.
On ultrasound, the cumulus oophorus appears as a cyst along the wall of the dominant follicle
Radiographic features
Ultrasound
- it may be seen as a small anechoic cyst (or group of cysts) around a dominant follicle
Differential diagnosis
- septated ovarian cyst: the stage of the menstrual cycle may help differentiate
References
- 1. Tanghe S, Van Soom A, Nauwynck H et-al. Minireview: Functions of the cumulus oophorus during oocyte maturation, ovulation, and fertilization. Mol. Reprod. Dev. 2002;61 (3): 414-24. doi:10.1002/mrd.10102 - Pubmed citation
- 2. Laing FC, Allison SJ. US of the ovary and adnexa: to worry or not to worry?. Radiographics. 2012;32 (6): 1621-39. doi:10.1148/rg.326125512 - Pubmed citation
- 3. Timor-Tritsch IE, Rottem S. Transvaginal sonography. Elsevier Science Ltd. ISBN:0444015779. Read it at Google Books - Find it at Amazon
- 4. Cacciatore B, Liukkonen S, Koskimies AI et-al. Ultrasonic detection of a cumulus oophorus in patients undergoing in vitro fertilization. J In Vitro Fert Embryo Transf. 1986;2 (4): 224-8. Pubmed citation
- 5. Kerin J. Ovulation Detection in the Human. Clin Reprod Fertil. 1982;1(1):27-54. - Pubmed
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