Cutaneous and subcutaneous metastases

Last revised by Dr Rohit Sharma on 18 Dec 2018

Cutaneous and subcutaneous metastases are not uncommon, occurring in ~5% (range 0.7-10.4%) of internal malignancies, and representing 2% of skin cancers. The Sister Mary Joseph nodule is a well known cutaneous metastasis.

Pathology

These metastases can come from hematogenous or lymphatic spread, or may result from seeding from a surgical procedure. Underlying primary malignancies include 1,2:

Radiographic features

Cutaneous and subcutaneous metastases can present as multiple small, usually <2 cm, masses or as a larger infiltrative mass 1.

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Cases and figures

  • Case 1: breast cancer
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  • Case 1: breast cancer
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