Cyclopia

Cyclopia refers to a rare fetal malformation characterised by a single palpebral fissure and a single midline orbit. This orbit may contain either a single globe or two separate globe.

The condition is thought to affect approximately 1 in 40,000 to 95,000 births (inclusive of stillbirths)  

It results from a deficient development of the superior precordial segment with an associated underdevelopment of the oro-nasal cavity 5. There is a severe error in prosencephalic development. 

Associations

Cyclopia can also occur as part of the spectrum of 

Possible associations
Antenatal ultrasound

May be seen with targeted imaging of the fetal face where a common orbit may be seen in the upper half of the face.  

Cyclopia is essentially incompatible with life 1

Derived from the Greek word cyclopes meaning ring-eyed 4.

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Article Information

rID: 13607
Tag: cases
Synonyms or Alternate Spellings:

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    Case 2: Cyclopia with proboscis
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