Cystadenocarcinoma of the rete testis

Last revised by Daniel J Bell on 6 Sep 2021

Cystadenocarcinoma of the rete testis is the malignant version of cystadenoma of the rete testis.  

Primarily a disease of older men (>60 years old), but has been noted in a wide age range (8-91 years).

Histologic evaluation requires exclusion of malignant mesothelioma or papillary serous carcinoma, which can be mimics.

Cystadenoma and cystadenocarcinoma of the rete testis cannot be radiologically distinguished, and prospective diagnosis of cystadenocarcinoma does not currently seem possible.

For sonographic appearance, see cystadenoma of the rete testis.  

~25% of tumors are associated with hydrocele.

Treatment and survival data are not robust due to the rarity of the tumor. Post orchiectomy patients still carry a guarded prognosis, unlike cystadenoma.

Radiologic differential diagnosis includes

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