Cystic fibrosis transmembrane regulator

Cystic fibrosis transmembrane regulator (CFTR) is a protein encoded by the CFTR gene on chromosome 7q31.2 and is responsible for regulating chloride passage across cell membranes. It is this gene that is mutated in patients with cystic fibrosis (CF) resulting in abnormally thick secretions. There are at least 6 classes of mutations, the commonest being ∂F508. 

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Article Information

rID: 8315
System: Chest
Tag: protein
Synonyms or Alternate Spellings:
  • Cystic fibrosis transmembrane regulating (CFTR) protein
  • Cystic fibrosis transmembrane regulator (CFTR)
  • CFTR

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