Delayed onset muscle soreness

Last revised by Henry Knipe on 27 Dec 2023

Delayed onset muscle soreness (DOMS) refers to the muscular pain and swelling that follows unaccustomed exertion.

Patients may have an ache in affected muscles with reduced strength 4.

DOMS is thought to occur from the reversible microstructural muscle injury that is followed by an inflammatory process and subsequent shifts of fluid and electrolytes. There is usually no permanent damage to muscle function. It can affect single or multiple muscles, or muscle groups 6

  • serum CK levels are often elevated

Most commonly DOMS presents as 5:

  • diffuse, well-defined hyperechoic regions within muscle
  • increased muscle size
  • minimal hyperemia
  • T2/STIR: affected muscles are high signal and this may persist for months following resolution of symptoms 4

For MRI appearances consider:

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.