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Deterministic effects describe a cause and effect relationship between ionizing radiation and certain side-effects. They are also known as non-stochastic effects to contrast them with chance-like stochastic effects (e.g. cancer induction).
These effects depend on dose, dose rate, dose fractionation, irradiated volume and type of radiation (linear energy transfer (LET)).
Deterministic effects have a threshold below which the effect does not occur. The threshold may be very low and may vary from person to person. However, once the threshold has been exceeded, the severity of an effect increases with dose.
There are practical threshold doses below which no significant changes are apparent and these thresholds should never be reached occupationally if sensible procedures are upheld.
skin erythema: 2-5 Gy
irreversible skin damage: 20-40 Gy
hair loss: 2-5 Gy
reduced fertility: 0.1-1.2 Gy (male sex, may be transient) 6, <2-7 Gy (female sex 8)
sterility: 4-6 Gy (male sex) 6,7, 4-20 Gy (female sex) 8,9
cataracts: 0.5 Gy1,5
lethality (whole body): 3-5 Gy
fetal abnormality: 0.1-0.5 Gy
- 1. W.E. Bolch, G. Dietze, N. Petoussi-Henss, M. Zankl. Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures:. (2015) Annals of the ICRP. 44 (1 Suppl): 91-111. doi:10.1177/0146645314562320 - Pubmed
- 2. Penelope Allisy-Roberts, Jerry R. Williams. Farr's Physics for Medical Imaging. ISBN: 9780702028441
- 3. Philip Palin Dendy, Brian Heaton. Physics for Diagnostic Radiology, Third Edition. ISBN: 9780750305914
- 4. Jerrold T. Bushberg. The Essential Physics of Medical Imaging. (2012) ISBN: 9781451118100
- 5. Stewart F, Akleyev A, Hauer-Jensen M et al. ICRP PUBLICATION 118: ICRP Statement on Tissue Reactions and Early and Late Effects of Radiation in Normal Tissues and Organs — Threshold Doses for Tissue Reactions in a Radiation Protection Context. Ann ICRP. 2012;41(1-2):1-322. doi:10.1016/j.icrp.2012.02.001 - Pubmed
- 6. Santaballa A, Márquez-Vega C, Rodríguez-Lescure Á et al. Multidisciplinary Consensus on the Criteria for Fertility Preservation in Cancer Patients. Clin Transl Oncol. 2021;24(2):227-43. doi:10.1007/s12094-021-02699-2 - Pubmed
- 7. Ståhl O, Eberhard J, Jepson K et al. Sperm DNA Integrity in Testicular Cancer Patients. Hum Reprod. 2006;21(12):3199-205. doi:10.1093/humrep/del292 - Pubmed
- 8. Wallace W, Thomson A, Kelsey T. The Radiosensitivity of the Human Oocyte. Hum Reprod. 2003;18(1):117-21. doi:10.1093/humrep/deg016 - Pubmed
- 9. Biedka M, Kuźba-Kryszak T, Nowikiewicz T, Żyromska A. Fertility Impairment in Radiotherapy. Wo. 2016;3(3):199-204. doi:10.5114/wo.2016.57814 - Pubmed
- 10. Penelope J. Allisy-Roberts, Jerry Williams. Farr's Physics for Medical Imaging. (2007) ISBN: 9780702028441. Page 26. - Google Books