Diffuse hepatic steatosis (grading)
Last revised by Jeremy Jones ◉ on 20 Sep 2021
Citation, DOI, disclosures and article data
Citation:
Goel A, Jones J, Di Muzio B, et al. Diffuse hepatic steatosis (grading). Reference article, Radiopaedia.org (Accessed on 21 Sep 2023) https://doi.org/10.53347/rID-33279
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rID:
33279
Article created:
6 Jan 2015, Ayush Goel ◉
Disclosures:
At the time the article was created Ayush Goel had no recorded disclosures.
View Ayush Goel's current disclosuresLast revised:
20 Sep 2021, Jeremy Jones ◉
Disclosures:
At the time the article was last revised Jeremy Jones had no recorded disclosures.
View Jeremy Jones's current disclosuresRevisions:
16 times, by 6 contributors - see full revision history and disclosures
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Synonyms:
- Grading of fatty liver
Grading of diffuse hepatic steatosis on ultrasound has been used to communicate to the clinician about the extent of fatty changes in the liver.
Grading
- grade I: diffusely increased hepatic echogenicity but periportal and diaphragmatic echogenicity is still appreciable
- grade II: diffusely increased hepatic echogenicity obscuring periportal echogenicity but diaphragmatic echogenicity is still appreciable
- grade III: diffusely increased hepatic echogenicity obscuring periportal as well as diaphragmatic echogenicity
Practical points
It is important not to fall into the pitfall that all diffusely echogenic livers are fatty, other pathologies may produce identical appearances, including cirrhosis.
Some suggest that visual grading of hepatic steatosis is subject to a wide interobserver and intraobserver variability 3.
There is also a histological three point scale for grading severity of non-alcoholic steatohepatitis 4. These two grading systems are not currently correlated.
References
- 1. Singh D, Das CJ, Baruah MP. Imaging of non alcoholic fatty liver disease: A road less travelled. Indian J Endocrinol Metab. 2013;17 (6): 990-5. doi:10.4103/2230-8210.122606 - Free text at pubmed - Pubmed citation
- 2. Perez NE, Siddiqui FA, Mutchnick MG et-al. Ultrasound diagnosis of fatty liver in patients with chronic liver disease: a retrospective observational study. J. Clin. Gastroenterol. 2007;41 (6): 624-9. doi:10.1097/01.mcg.0000225680.45088.01 - Pubmed citation
- 3. Strauss S, Gavish E, Gottlieb P et-al. Interobserver and intraobserver variability in the sonographic assessment of fatty liver. AJR Am J Roentgenol. 2007;189 (6): W320-3. doi:10.2214/AJR.07.2123 - Pubmed citation
- 4. Brunt EM, Janney CG, Di Bisceglie AM et-al. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am. J. Gastroenterol. 1999;94 (9): 2467-74. doi:10.1111/j.1572-0241.1999.01377.x - Pubmed citation
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