Diffuse peritoneal leiomyomatosis

Last revised by Dr Mostafa El-Feky on 27 Mar 2020

Diffuse or disseminated peritoneal leiomyomatosis, also known as leiomyomatosis peritonealis disseminata, is an exceedingly rare benign disorder characterized by multiple vascular leiomyomas growing along the submesothelial tissues of the abdominopelvic peritoneum.

It is usually discovered incidentally in women of reproductive age.

A spectrum of features can be seen ranging from multiple solid subcentimeter nodules like those in peritoneal carcinomatosis to large solid masses on both ultrasound and CT. These masses may show homogeneous or heterogeneous attenuation with a variable enhancement pattern similar to that of uterine leiomyomas.

May show multiple masses with signal intensity similar to that of skeletal muscle and smooth muscle on both T1WI and T2WI. Homogeneous enhancement following the administration of contrast material.

The condition was first defined by H D Taubert et al. in 1965 3.

General considerations include:

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Cases and figures

  • Case 1
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