Diffuse T1 vertebral bone marrow signal loss has a number of causes. T1-weighted imaging without fat suppression is one of the most important sequences for distinguishing between normal and abnormal bone marrow. Given the homogeneity, this appearance can often be difficult to spot as abnormal.
- 1. Bone Marrow Signal Alteration in the Spine and Sacrum ,Suzanne S. Long, Corrie M. Yablon, and Ronald L. Eisenberg, American Journal of Roentgenology 2010 195:3, W178-W200
- 2. Shah LM, Hanrahan CJ. MRI of spinal bone marrow: part I, techniques and normal age-related appearances. AJR. American journal of roentgenology. 197 (6): 1298-308. doi:10.2214/AJR.11.7005 - Pubmed