Diffusion kurtosis imaging (DKI) is an advanced neuroimaging modality which is an extension of diffusion tensor imaging by estimating the kurtosis (skewed distribution) of water diffusion based on a probability distribution function. It provides a high order diffusion of water distribution and analyses and also quantifies the diffusion restriction. The kurtosis is a general, dimensionless statistic for quantifying non-gaussianity – that is, the difference from a normal/random distribution – of any distribution. It may be used in the imaging of stroke4.
- imaging of cerebral ischaemia
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- 4. Hui ES, Fieremans E, Jensen JH, Tabesh A, Feng W, Bonilha L, Spampinato MV, Adams R, Helpern JA. Stroke assessment with diffusional kurtosis imaging. Stroke. 2012 Nov;43(11):2968-73. doi: 10.1161/STROKEAHA.112.657742. Epub 2012 Aug 28.Pubmed citation