The disappearing basal ganglia sign is one of the early signs of an MCA infarction. It is defined as the loss of delineation of the basal ganglia, due to blurring of their grey-white matter interface and hypoattenuation, consequent to cytotoxic oedema at the time of an ischaemic event.
It is best appreciated when compared to the contralateral side.
Other associated early signs of MCA infarction are:
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