Disappearing basal ganglia sign

Last revised by Rohit Sharma on 14 Feb 2024

The disappearing basal ganglia sign is one of the early signs of a middle cerebral artery (MCA) infarction. It is defined as the loss of delineation of the basal ganglia, due to blurring of their grey-white matter interface and hypoattenuation, consequent to cytotoxic edema at the time of an ischemic event.

It is best appreciated when compared to the contralateral side.

Other associated early signs of MCA infarction are:

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