Distal cholangiocarcinoma staging is defined according to the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below 1. These criteria apply to cancers of the distal (extrahepatic) bile ducts, while cancers of the intrahepatic and perihilar bile ducts are staged differently.
On this page:
Primary tumour (T)
- TX: primary tumour cannot be assessed
- Tis: carcinoma in situ/high-grade dysplasia
- T1: tumour invades the bile duct wall with depth <5 mm
- T2: tumour invades the bile duct wall with depth 5–12 mm
- T3: tumour invades the bile duct wall with depth >12 mm
- T4: tumour involves the coeliac axis, superior mesenteric artery, and/or common hepatic artery
Regional lymph node (N)
- NX: regional lymph nodes cannot be assessed
- N0: no regional lymph node metastasis
- N1: 1-3 positive regional lymph nodes
- N2: 4 or more positive regional lymph nodes
Distant metastases (M)
- cM0: no evidence of metastases
- cM1: distant metastasis
- pM1: distant metastasis, microscopically confirmed
Stage groups
-
stage 0
- Tis, N0, M0
-
stage I
- T1, N0, M0
-
stage IIA
- T1, N1, M0
- T2, N0, M0
-
stage IIB
- T2, N1, M0
- T3, [N0, N1], M0
-
stage IIIA
- [T1, T2, T3], N2, M0
-
stage IIIB
- T4, [N0, N1, N2], M0
-
stage IV
- [Any T], [Any N], M1
Unable to process the form. Check for errors and try again.