A dizygotic (DZ) twin pregnancy is a type of twin pregnancy where two separate ova are independently fertilised by two separate sperm resulting the two separate zygotes. These twins are also known as fraternal twins or non-identical twins. They may or may not be of the same gender.
Dizygotic twins are the most common type of multifetal pregnancy, accounting for approximately 70%. There is significant racial variation in incidence. The overall incidence is increasing due to the use of in vitro fertilisation (IVF).
A dizygotic twin pregnancy always results in dichorionic diamniotic pregnancies. This feature alone cannot be used to distinguish dizygotic from monozygotic pregnancies as approximately 20% of monozygotic pregnancies will also be dichorionic diamniotic.
Risk factors for dizygotic pregnancy:
- in vitro fertilisation (IVF)
- advanced maternal age
- family history
- ethnicity (e.g. Nigerian 3)
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