The doughnut sign refers to the bone scan pattern whereby there is increased uptake peripherally with a photopenic centre. This appearance may be seen in a number of cystic lesions including:
The doughnut sign is a non-specific sign, and can also be seen in chondrosarcoma, telangiectatic osteosarcoma and any other lesions that show aneurysmal bone cyst changes within. It has also been described in non-traumatic avascular necrosis.
- 1. Imaging of Bone Tumors and Tumor Like Lesions. Springer. (2009) ISBN:3540779841. Read it at Google Books - Find it at Amazon
- 2. Murphey MD, Nomikos GC, Flemming DJ et-al. From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic correlation. Radiographics. 2001;21 (5): 1283-309. Radiographics (full text) - Pubmed citation
- 3. Seven B, Varoglu E, Alper F et-al. Aneurysmal bone cyst of the second metatarsal: three-phase bone scan findings and radiological assessment. Hell J Nucl Med. 2009;11 (3): 189-90. Pubmed citation