Doughnut sign on bone scintigraphy

Last revised by Yuranga Weerakkody on 18 Sep 2024

The doughnut sign refers to the bone scintrigraphy pattern where there is increased uptake peripherally with a photopenic center. This appearance may be seen in a number of cystic lesions including:

The doughnut sign is a non-specific sign, and can also be seen in chondrosarcoma, telangiectatic osteosarcoma and any other lesions that show aneurysmal bone cyst changes within. It has also been described in non-traumatic osteonecrosis.

See also