Drug and toxin induced pulmonary hypertension is one of the causes of pulmonary arterial hypertension. It falls under group 1.3 under the Dana point classification system of pulmonary hypertension.
Pathology
A wide range of different drugs have been associated with developing pulmonary hypertension:
- appetite suppressant drugs: have been withdrawn from the market
- aminorex
- fenfluramine derivatives
- benfluorex
- phenylpropanolamine
- amphetamines
- phentermine
- mazindol
- dasatinib: a dual Src/Abl kinase inhibitor, used in the treatment of chronic myelogenous leukemia
- interferon: possible
- possible agents
- phenylpropanolamine
- L-tryptophan
- certain selective serotonin reuptake inhibitors: pergolide
Radiographic features
Refer to the main article on pulmonary hypertension.
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