Dual-energy CT (clinical applications)
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At the time the article was created Andrew Murphy had no recorded disclosures.View Andrew Murphy's current disclosures
At the time the article was last revised Joel Matthew Davies had no financial relationships to ineligible companies to disclose.View Joel Matthew Davies's current disclosures
Dual-energy CT or multispectral CT is becoming increasingly common in clinical practice due to the rapid rise in computer technology and expanding literature exhibiting vast advantages over conventional single energy CT.
The clinical practice, adaptation and techniques of dual-energy CT is broken into individual articles:
automated bone removal in CT angiography 2
decrease metal device artifact 7
detection of endoleaks 7
blood pool imaging 2
detection of pulmonary embolism
detection of myocardial ischemia
characterization of renal stones 2
characterization of renal cysts and masses 2-4
differentiation of hemorrhage from iodinated contrast
quantification of iodine leak in traumatic hemorrhagic contusions
identification of silicone leaks from breast implants 2
improved tumor conspicuity of breast cancers relative to conventional CT, with the potential determination of prognostic biomarkers such as ER and PR status 6
detection of bone marrow edema
detection and quantification of urate crystals in gout
reduction of metal artifact 7
pancreatic diseases 5
detection of pulmonary thromboembolism; structural as well as functional information is obtained through iodine maps of pulmonary perfusion 7
assessment of a solitary pulmonary nodule to determine malignancy status 7,8
- 1. Fornaro J, Leschka S, Hibbeln D, Butler A, Anderson N, Pache G, Scheffel H, Wildermuth S, Alkadhi H, Stolzmann P. Dual- and multi-energy CT: approach to functional imaging. (2011) Insights into imaging. 2 (2): 149-159. doi:10.1007/s13244-010-0057-0 - Pubmed
- 2. McCollough CH, Leng S, Yu L, Fletcher JG. Dual- and Multi-Energy CT: Principles, Technical Approaches, and Clinical Applications. (2015) Radiology. 276 (3): 637-53. doi:10.1148/radiol.2015142631 - Pubmed
- 3. Mileto A, Nelson RC, Paulson EK, Marin D. Dual-Energy MDCT for Imaging the Renal Mass. (2015) AJR. American journal of roentgenology. 204 (6): W640-7. doi:10.2214/AJR.14.14094 - Pubmed
- 4. Kessner R, Große Hokamp N, Ciancibello L, Ramaiya N, Herrmann KA. Renal cystic lesions characterization using spectral detector CT (SDCT): Added value of spectral results. (2019) The British journal of radiology. 92 (1100): 20180915. doi:10.1259/bjr.20180915 - Pubmed
- 5. George E, Wortman JR, Fulwadhva UP, Uyeda JW, Sodickson AD. Dual energy CT applications in pancreatic pathologies. (2017) The British journal of radiology. 90 (1080): 20170411. doi:10.1259/bjr.20170411 - Pubmed
- 6. Moon J Il, Choi BH, Baek HJ, Ryu KH, Park SE, Ha JY, et al. Comprehensive analyses with radiological and biological markers of breast cancer on contrast-enhanced chest CT: a single center experience using dual-layer spectral detector CT. Eur Radiol. 2020 May 1;30(5):2782–90.
- 7. 1. Cicero G, Ascenti G, Albrecht MH, Blandino A, Cavallaro M, D’Angelo T, et al. Extra-abdominal dual-energy CT applications: a comprehensive overview. Radiol Medica. 2020 Apr 1;125(4):384–97.
- 8. Wu L, Cao G, Zhao L, Tang K, Lin J, Miao S, et al. Spectral CT Analysis of Solitary Pulmonary Nodules for Differentiating Malignancy from Benignancy: The Value of Iodine Concentration Spatial Distribution Difference. Biomed Res Int. 2018;2018:4830659.