Dual-energy digital mammography is a complementary breast imaging modality.
The technique consists of high-energy and low-energy digital mammograms after administration of iodinated contrast agent.
Breast is exposed to low- and high-energy X-ray beams during a single breast compression in MLO projection. The breast is then released from compression, and the contrast agent injected. After a delay of about 3 minutes, the breast is compressed again, and the low- and high-energy exposures are repeated to create pre- and post-contrast dual-energy images, to evaluate the kinetics of uptake and washout .
The images are subtracted, cancelling the soft-tissue contrast common to the two images and isolating the iodine signal in the region of angiogenesis. Low- and high-energy acquisitions are chosen to maximize and minimize, respectively, the ratio of the attenuation of the breast tissue to that of the iodine.
For the high-energy beam is used a combination of rhodium target with aluminum filter, while for the low-energy beam the combination of molybdenum target with molybdenum filter.
Dual-energy enhanced mammography is a cheap technique useful in identification of lesions in dense breasts, capable of demonstrating cancers that are not visible at standard mammography.
- 1. Asaga T, Masuzawa C, Yoshida A et-al. Dual-energy subtraction mammography. J Digit Imaging. 1995;8 (1 Suppl 1): 70-3. - Pubmed citation
- 2. Taibi A, Fabbri S, Baldelli P et-al. Dual-energy imaging in full-field digital mammography: a phantom study. Phys Med Biol. 2003;48 (13): 1945-56. Phys Med Biol (link) - Pubmed citation
- 3. Lewin JM, Isaacs PK, Vance V et-al. Dual-energy contrast-enhanced digital subtraction mammography: feasibility. Radiology. 2003;229 (1): 261-8. doi:10.1148/radiol.2291021276 - Pubmed citation